Spinal muscular atrophy in Maine Coons in cats
Also known as SMA.
An inherited disease of the Maine Coon in which the nerve cells that move the back leg muscles die. It appears at a few months of age, is not painful and does not progress to become fatal.
- Is it urgent?
- Not usually
- Spreads to other cats
- No
- Spreads to people
- No
- Origin
- Inherited
- Typical cost in Spain
- Genetic test, €30–70.
Symptoms
- From 3–4 months, a swaying gait at the hips
- Struggles to jump
- Thin back legs
- Crouched posture
Causes
A recessive deletion in the LIX1 and LNPEP genes.
How it is diagnosed
Genetic testing.
Treatment
There is no treatment. An indoor life and an adapted home.
No doses, on purpose: any medicine must be prescribed by your vet for your cat.
Prognosis
Affected cats usually live well indoors, although they do not jump.
Prevention
Genetic testing of breeding cats.
Breeds at higher risk
It is described more often in these breeds. That does not mean all of their cats will have it, nor that a moggy is free of it.
Frequently asked questions
What causes spinal muscular atrophy in Maine Coons?
A recessive deletion in the LIX1 and LNPEP genes.
Can spinal muscular atrophy in Maine Coons be cured?
Affected cats usually live well indoors, although they do not jump. There is no treatment. An indoor life and an adapted home.
How much does it cost to treat spinal muscular atrophy in Maine Coons?
As a guide for Spain in 2026: Genetic test, €30–70. Prices vary a lot between clinics and cities, and out-of-hours emergencies cost more.
Which breeds are most at risk?
It is described more often in Maine Coon. That does not mean every cat of those breeds will have it, nor that a moggy is free of it.
More in inherited breed conditions
Educational content from Michipedia. It does not replace diagnosis or treatment by a vet: if you have any doubt about your cat's health, ask. Costs are a guide for Spain in 2026.